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Cake day: March 13th, 2024

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  • Lots of stretching here. The paper uses simulations of microtubules to show quantum effects when tryptophan residues are excited by UV light. The paper only did simulations of microtubules, and those simulations did not include the bends and many many dynein molecules found on microtubules. The reason this is important is that researchers have been hitting every biomolecule with UV excitation for decades, including microtubules, and have never observed this effect.

    A key finding missing from this video is that microtubules are dynamic. They are constantly disassembling and reassembling and recycling components. This occurs at very short timescales. Also, they do not bridge cell membranes. If information is passing through networks of microtubules, it is constantly disrupted and not affecting other cells. Synapses do handle cell-cell information transfer (where the role of microtubules is already well studied and not quantum in nature). Why would quantum microtubule information be limited to a single cell? Maybe it could influence coordinated assembly and disassembly at the termini, but the authors offer no evidence that there is any chemical effect of this quantum phenomenon, which would be required to change anything about how those enzymes behave.

    We already know of a mechanism by which information is transported across microtubules: physical transport of signalling molecules. They are walked (quite literally, dynein is cool) along the microtubules to different sites in the cell. No quantum effects needed to explain this phenomenon.







  • So we should abandon diplomacy precisely when it is needed most? When we withdraw our support and Iran and Egypt join the conflict, will it be easier to stomach the killing of even more children in more nations? After we cede our influence in the middle east and China expands its influence to fill the vacuum, we will be able to honor our treaty with Taiwan after an emboldened China begins bombing and killing their children?

    This is the macabre calculus of geopolitics. This is the risk of reactionary policy. All of this is a hypothetical worse case scenario, but one thing is certain: if we withdraw our support, Israel will lose any incentive to stop the killing. More will die. And that would be the best case scenario.


  • I am really disappointed with the discourse concerning Biden’s handling of the most recent Israeli-Palestinian conflict. Everyone is acting like Biden invented our alliance with Israel and is somehow personally responsible for our support of Israel. Geopolitical alliances are complicated matters that touch everything from international reputation to national security. They are fostered over decades. We have obligations to Israel that precede Biden and the recent conflict.

    I understand the moral positions people are taking, and I agree that a genocide is taking place. But with anything geopolitical, these issues must be approached without hard lines and moral absolutism, because those ideals are what both sides are using to justify the atrocities we are witnessing. They both feel morally justified, and that the other side has crossed some hard lines. That is how diplomacy breaks down.

    Those of you that want to see an end to the conflict need to understand that the official US position at this moment is aligned with you. But so many of you are proposing “simple” solutions that will not achieve that outcome. If we end support for Israel, they will not stop the genocide. What we will lose is leverage in negotiating peace and we will weaken the alliance with Israel, and the genocide will continue unhindered by US calls for restraint. You may argue that Israel relies on this alliance for security, and that is true, but you assume that other super powers would not jump at the chance to replace the US as a close ally to a nuclear power in the middle east.

    Let’s not forget how rash reactionary approaches to geopolitics threatened the NATO alliance during the Trump presidency. Our allies are already doubting if the US will honor the treaty, and this doubt extends to Taiwan, too. Weakening these alliances gives power to our enemies, full stop. Do you want to see war break out in the Pacific? Russia to expand its empire eastward? The Israel-Palestine conflict to extend to other Arab nations? Damaging these alliances will cause more war, not less.

    Outrage against Israel is justified. But look past your nose before you jeopardize our key alliances. Diplomacy is slow and frustrating, but it is better than more war.