Do you have anything to offer regarding TPO, then? You appear to have a high opinion of your knowledge of the topic, so please share.
Here’s what I’ve found using DDG:
https://www.cir-safety.org/sites/default/files/SLR_TrimethylbenzoylDiphenylphosphineOxide_122024.pdf
Pages 6-9 Include:
“Some of the adverse effects observed in this study
include body weight reduction, abnormalities in clinical chemistry, increased liver, kidney, brain, adrenal gland, and testes
weight, and marked diffuse atrophy of the testicular parenchyma (compared to controls; these effects were observed in the
mid- and high-dose groups). Testicular atrophy, decreased mean testes weight, and decreased mean body weights (compared
to controls) were also observed in a different 90-d assay performed in male Wistar rats (10/group) given Trimethylbenzoyl
Diphenylphosphine Oxide (purity 99.3%; 1000 mg/kg bw/d) in a 0.5% carboxymethylcellulose aqueous solution via gavage”
I mean from what that study describes there might be some toxic properties at high-ish doses: the 60mg/kg/day showed no effects. That would mean 3.6g for a 60kg human sized rat taken orally, which is quite a lot to accidentally eat. I think the limit is 5% TPO in the nail products, so you’d have to be trying to ingest it.
But my original comment is that I don’t think there’s much relation with phosphine.
Do you have anything to offer regarding TPO, then? You appear to have a high opinion of your knowledge of the topic, so please share.
Here’s what I’ve found using DDG: https://www.cir-safety.org/sites/default/files/SLR_TrimethylbenzoylDiphenylphosphineOxide_122024.pdf Pages 6-9 Include: “Some of the adverse effects observed in this study include body weight reduction, abnormalities in clinical chemistry, increased liver, kidney, brain, adrenal gland, and testes weight, and marked diffuse atrophy of the testicular parenchyma (compared to controls; these effects were observed in the mid- and high-dose groups). Testicular atrophy, decreased mean testes weight, and decreased mean body weights (compared to controls) were also observed in a different 90-d assay performed in male Wistar rats (10/group) given Trimethylbenzoyl Diphenylphosphine Oxide (purity 99.3%; 1000 mg/kg bw/d) in a 0.5% carboxymethylcellulose aqueous solution via gavage”
I mean from what that study describes there might be some toxic properties at high-ish doses: the 60mg/kg/day showed no effects. That would mean 3.6g for a 60kg human sized rat taken orally, which is quite a lot to accidentally eat. I think the limit is 5% TPO in the nail products, so you’d have to be trying to ingest it.
But my original comment is that I don’t think there’s much relation with phosphine.